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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP1G2 All Species: 39.09
Human Site: T350 Identified Species: 71.67
UniProt: O75843 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75843 NP_003908.1 785 87117 T350 A V Q R H R P T V V E C L R E
Chimpanzee Pan troglodytes XP_001163717 785 87058 T350 A V Q R H R P T V V E C L R E
Rhesus Macaque Macaca mulatta XP_001109007 785 86931 T350 A V Q R H R P T V V D C L Q E
Dog Lupus familis XP_537377 787 87286 T350 A V Q R H R P T V V E C L R E
Cat Felis silvestris
Mouse Mus musculus O88512 791 87846 T350 A V Q R H R S T V V E C L Q E
Rat Rattus norvegicus P18484 938 104026 V372 V K T H I E T V I N A L K T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509435 822 91369 T349 A V Q R H R S T I V D C L K D
Chicken Gallus gallus NP_001006132 821 91444 T352 A V Q R H R S T I V D C L K D
Frog Xenopus laevis NP_001083997 812 90423 T349 A V Q R H R S T I V D C L K D
Zebra Danio Brachydanio rerio NP_955976 819 90933 T349 A V Q R H R S T I V D C L K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91926 940 105602 V373 V K K H Q E V V I L S M K M E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792773 959 106235 T460 A V Q R H R S T I V D C L K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12028 832 93606 F379 A V Q R H R K F I S H C L Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97 90.3 N.A. 86.4 24 N.A. 60.4 59.9 59.3 60.3 N.A. 24 N.A. N.A. 42
Protein Similarity: 100 99.8 97.8 94.2 N.A. 91.7 44.5 N.A. 75.5 75.4 76.4 75.5 N.A. 44.2 N.A. N.A. 58.8
P-Site Identity: 100 100 86.6 100 N.A. 86.6 6.6 N.A. 66.6 66.6 66.6 66.6 N.A. 6.6 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 13.3 N.A. 93.3 93.3 93.3 93.3 N.A. 26.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 85 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 85 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 47 0 0 0 47 % D
% Glu: 0 0 0 0 0 16 0 0 0 0 31 0 0 0 54 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 16 85 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 62 0 0 0 0 0 0 % I
% Lys: 0 16 8 0 0 0 8 0 0 0 0 0 16 39 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 0 8 85 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 85 0 8 0 0 0 0 0 0 0 0 24 0 % Q
% Arg: 0 0 0 85 0 85 0 0 0 0 0 0 0 24 0 % R
% Ser: 0 0 0 0 0 0 47 0 0 8 8 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 8 77 0 0 0 0 0 8 0 % T
% Val: 16 85 0 0 0 0 8 16 39 77 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _